JBS Products: Crystallization Screens


JBScreen Pi-Minimal
The Pi-minimal Screen was developed at the MRC Laboratory of Molecular Biology (Cambridge, UK) for efficient crystallization screening of soluble proteins. The approach is based on incomplete factorial design.
JBScreen Pi-PEG
The Pi-PEG Screen was developed at the MRC Laboratory of Molecular Biology (Cambridge, UK). It has been designed for efficient crystallization screening of integral membrane proteins benefiting from the experience of membrane protein crystallization at the MRC.
JBScreen Classic
JBScreen Classic Kits 1-10 cover 240 (10 kits × 24 conditions each) of the most successful conditions for protein crystallization. Their compositions were obtained by examining the published crystallization conditions of thousands of proteins. JBScreen contains the statistically selected most successful buffers that yielded protein crystals suitable for X-ray diffraction.
JBScreen Basic
Based on the classic sparse matrix crystallization screen first published by Jancarik and Kim in 1991, JBScreen Basic contains 96 unique reagent mixtures for screening a wide range of pH and various salts and precipitants.
JBScreen Membrane
Optimized for hydrophobic and membrane proteins.
JBScreen Kinase
A highly effective crystallization screen based on data analyses of published kinase structures.
JBScreen PEG/Salt
For efficient screening of PEG 3350 and PEG 5000 MME versus 48 different salts.
JBScreen Cryo
An advanced cryo screen.
JBScreen PACT++
Systematic screen for pH, anion, cation testing in the presence of polyehtylene glycol.
JBScreen JCSG++
Optimized sparse matrix screen developed by the Joint Center for Structural Genomics (JCSG).
JBScreen Phosphatase
A highly specialized crystallization screen ideally suited for phosphatases. 96 conditions have been selected from a comprehensive survey of successfully crystallized phosphatases.
JBScreen Nuc-Pro
AA highly effective sparse matrix screen based upon extensive screening of the PDB, with focus on entries by structural genomic initiatives, the BMCD and other protocols.
JBScreen Pentaerythritol
A systematic crystallization screen based on pentaerythritol polymers as precipitants developed by Ulrike Demmer from the Max-Planck-Institute for Biophysics in Frankfurt


All screens are available either in kits of 24 - 10 ml vials or, for high-throughput screening (HTS), in 96-well deep well plates with 1.0 or 1.7 ml per well.