Gentaur's Products: Innovative and High Quality Peptide Toxins
ω-Conotoxin MVIIA / Omega conotoxin MVIIA
(Ziconotide)
Catalog N : 08CON001
ω-Conotoxin MVIIA: toxin properties
ω-Conotoxin MVIIA has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). This toxin blocks N-type calcium channels (Cav2.2/CACNA1B). ω-conotoxin MVIIA is available under the name Prialt by Neurex. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals.
Product Specification
AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16-Thr-Gly-Ser-Cys20-Arg-Ser-Gly-Lys-Cys25-NH2
(Disulfide bonds between Cys1-Cys16, Cys8-Cys20 and Cys15-Cys25)
Length (aa): 25
Formula: C102H172N36O32S7
Molecular Weight: 2639.18 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [107452-89-1]
Source: Synthetic
Purity rate: > 97 %
Price & Quantities
| Reference # | Product name | Quantity (mg) |
| 08CON001-00100 | ω-Conotoxin MVIIA | 0.1 |
| 08CON001-00500 | ω-Conotoxin MVIIA | 0.5 |
| 08CON001-01000 | ω-Conotoxin MVIIA | 1 |
Other quantities available upon request
