Gentaur's Products: Innovative and High Quality Peptide Toxins
ADWX-1
ADWX-1: inhibits Kv1.3 channel
ADWX-1 is an optimised synthetic analog of the scorpion peptide BmKTx. ADWX-1 is known to block voltage gated Kv1.3 channel with a high affinity (IC50 = 1.89 pM) and selectivity (340 fold greater affinity than for voltage-dependent ).ADWX1 is an interesting therapeutic candidate to treat auto-immune disorders such as multiple sclerosis, type-1 diabetes, rheumatoid arthritis and psoriasis. This peptide is a valuable tool for studying the structure-function of Kv1.3 channel and auto-immunity pathways.
Product Specifications
AA sequence: Val-Gly-Ile-Asn-Val-Lys-Cys7-Lys-His-Ser-Arg-Gln-Cys13-Leu-Lys-Pro-Cys17-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys27-Thr-Asn-Gly-Lys-Cys32-His-Cys34-Thr-Pro-Lys-OH
Disulfide bonds between: Cys7-Cys27, Cys13-Cys32, Cys17-Cys34
Length (aa): 37
Formula: C169H281N57O46S7
Molecular Weight: 4071.90 Da
Purity rate: > 98%
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: not available
Source: Synthetic
Price & Quantities
| Reference # | Product name | Quantity (mg) |
| 13ADW001-00100 | ADWX-1 | 0.1 |
| 13ADW001-00500 | ADWX-1 | 0.5 |
| 13ADW001-01000 | ADWX-1 | 1 |
Other quantities available upon request
