Gentaur's Products: Innovative and High Quality Peptide Toxins
GsAF-I
Peptide properties
GsAF-I (also termed β-theraphotoxin-Gr1b) was originally isolated from the venom of Grammostola rosea spider. This peptide toxin is reported to block the following voltage-gated sodium channels: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with respective IC50 values of 0.4, 0.6, 1.3, 0.3, 1.2 and 0.04 µM. In addition, the toxin blocks the hERG1 isoform with an IC50 value of 4.8 µM.
Product specifications
AA sequence: Tyr-Cys2-Gln-Lys-Trp-Leu-Trp-Thr-Cys9-Asp-Ser-Glu-Arg-Lys-Cys15-Cys16-Glu-Asp-Met-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Lys-Arg-Leu-NH2
(Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25)
Length (aa): 29
Formula: C160H245N47O41S7
Molecular Weight: 3707.48 Da
Appearance: White lyophilized solid
Solubility: aqueous buffer
CAS number: not available
Source: Synthetic
Prices & Quantities
| Reference # | Prodcut name | Quantity (mg) |
| 12GSF001-00100 | GsAF-I | 0.1 |
| 12GSF001-00500 | GsAF-I | 0.5 |
| 12GSF001-01000 | GsAF-I | 1 |
Other quantities available upon request
