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Gentaur's Products: Innovative and High Quality Peptide Toxins


 

Waglerin 1



Catalog N: 12WAG001

Peptide properties

Waglerin 1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler's pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of muscle nicotinic acetylcholine receptors. Waglerin 1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin 1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin 1 are currently used in cosmetics to reduce wrinkles.

Product specifications

AA sequence:  Gly-Gly-Lys-Pro-Asp-Leu-Arg-Pro-Cys9-His-Pro-Pro-Cys13-His-Tyr-Ile-Pro-Arg-Pro-Lys-Pro-Arg-OH
(Disulfide bonds between Cys9-Cys13)
Length (aa): 22
Formula: C112H175N37O26S2 
Molecular Weight: 2520 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: NA
Source: Synthetic

Price & quantities


Reference # Product name Quantity (mg)
12WAG001-01000 Waglerin 1 1
12WAG001-55000 Waglerin 1 5 x 1

Other quantities available upon request