Gentaur's Products: Innovative and High Quality Peptide Toxins
GsMTx4
Description
GsMTx4 has been isolated from the venom of the spider Grammostola rosea. This cationic hydrophobic polypeptide blocks mechanosensitive ion channels such as TRPC1 or TRPC6, without having any effect on whole-cell voltage-sensitive currents. This toxin acts by perturbing the interface between the channel and the lipid bilayer without necessarily being in physical contact with the channel. GsMTx4 also demonstrated to active TRPA1 channel at 1µM concentration.
Product Specifications
AA sequence: H-Gly-Cys2-Leu-Glu-Phe-Trp-Trp-Lys-Cys9-Asn-Pro-Asn-Asp-Asp-Lys-Cys16-Cys17-Arg-Pro-Lys-Leu-Lys-Cys23-Ser-Lys-Leu-Phe-Lys-Leu-Cys30-Asn-Phe-Ser-Phe-NH2
(Disulfide bonds between Cys2-Cys17, Cys9-Cys23 and Cys16-Cys30)
Length (AA): 34
Formula: C185H273N49O45S6
Molecular Weight: 4095.2 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number:
Source: Synthetic
Purity rate: > 97 %
Price & Quantities
| Reference # | Product name | Quantity (mg) |
| 08GSM001-00050 | GsMTx4 | 0.05 |
| 08GSM001-00100 | GsMTx4 | 0.1 |
| 08GSM001-00500 | GsMTx4 | 0.5 |
Other quantities available upon request
