Gentaur's Products: Innovative and High Quality Peptide Toxins
SNX482
SNX 482: toxin properties
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). This toxin modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene). SNX-482 antagonizes channel activation by inducing a depolarizing shift in the activation potential, thus preventing the channel from undergoing normal membrane depolarization. SNX-482 acts rapidly and maintains its effect.
Product Specification
AA sequence: H-Gly-Val-Asp-Lys-Ala-Gly-Cys7-Arg-Tyr-Met-Phe-Gly-Gly-Cys14-Ser-Val-Asn-Asp-Asp-
Cys20-Cys21-Pro-Arg-Leu-Gly-Cys26-His-Ser-Leu-Phe-Ser-Tyr-Cys33-Ala-Trp-Asp-Leu-Thr-Phe-Ser-Asp-OH
(Disulfide bonds between Cys7-Cys21, Cys14-Cys26 and Cys20-Cys33)
Length (aa): 41
Formula: C192H274N52O60S7
Molecular Weight: 4496.42 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: 203460-30-4
Source: Synthetic
Purity rate: > 95 %
Price & Quantities
| Reference # | Product name | Quantity (mg) |
| 08SNX001-00050 | SNX482 | 0.05 |
| 08SNX001-00100 | SNX482 | 0.1 |
Other quantities available upon request
