Insulin Receptor Pathway


The insulin receptor pathway plays a key role in the regulation of metabolic homeostasis. The insulin receptor acts as a tyrosine phosphatase and, upon insulin binding, initiates a phosphorylation cascade that increases the concentration of glucose transporter molecules in muscle and adipose tissue. Further regulation is maintained through the link to the AKT/PI3K pathways which also promotes conversion of glucose in glycogen for cellular storage.

This free bioinformatics tool is designed to facilitate scientific exploration of related genes, diseases and pathways based on co-citations.