Oxidative Stress


Oxidative stress describes the steady state level of oxidative damage in a cell, tissue, or organ, caused by the reactive oxygen species (ROS). This damage can have a widespread effect on an entire organism, or on just a single molecule. It is caused by an imbalance between the production of reactive oxygen and a biological system's ability to readily detoxify the reactive intermediates or easily repair the resulting damage. All forms of life maintain a reducing environment within their cells through a constant input of metabolic energy which is preserved by enzymes. Disturbances in this normal redox state can cause toxic effects through the production of cell damaging peroxides and free radicals.

Research on human oxidative stress has led to links to many diseases such as atherosclerosis, Parkinson's disease and Alzheimer's disease and it may also be important in ageing. At the same time, reactive oxygen species can also be beneficial, as they are used by the immune system as a way to attack and kill pathogens.

Product

Category

Clone #

Catalog #

Size

Description

Research Area

Ambroxol HCl

Small Molecules

N/A

SIH-153-50MG

50mg

Free radical scavenger

Oxidative Stress

Ambroxol HCl

Small Molecules

N/A

SIH-153-500MG

500mg

Free radical scavenger

Oxidative Stress

bis-BHT

Small Molecules

N/A

SIH-154-100MG

100mg

Phenolic antioxidant

Oxidative Stress

bis-BHT

Small Molecules

N/A

SIH-154-500MG

500mg

Phenolic antioxidant

Oxidative Stress

DMPO

Small Molecules

N/A

SIH-324-25MG

25mg

Nitrone adduct formation

Oxidative Stress

DMPO

Small Molecules

N/A

SIH-324-125MG

125mg

Nitrone adduct formation

Oxidative Stress

DMPO Antibody

Antibodies

N1664A

SMC-189D

100ug

 

Oxidative Stress

DMPO Antibody: Biotin

Antibodies

N1664A

SMC-191D

100ug

 

Oxidative Stress

DMPO Antibody: FITC

Antibodies

N1664A

SMC-190D

100ug

 

Oxidative Stress

DNA Damage, 8-OH-dG StressXpress® EIA Kit

Kits

N/A

SKT-120-96

96-well

8-OHdG detection

Oxidative Stress

DNA Damage, 8-OH-dG StressXpress® EIA Kit

Kits

N/A

SKT-120-480

5x96 well

8-OHdG detection

Oxidative Stress

DNA/RNA Damage Antibody

Antibodies

15A3

SMC-155C

25ug

 

Oxidative Stress, Post-translational Modifications

DNA/RNA Damage Antibody

Antibodies

15A3

SMC-155D

100ug

 

Oxidative Stress, Post-translational Modifications

FIH Antibody

Antibodies

FIH 162c

SMC-182D

100ug

 

Cell Signaling, Oxidative Stress

HIF1 alpha Antibody

Antibodies

ESEE122

SMC-184C

25ug

 

Cell Signaling, Oxidative Stress

HIF1 alpha Antibody

Antibodies

ESEE122

SMC-184D

100ug

 

Cell Signaling, Oxidative Stress

HIF2 alpha Antibody

Antibodies

EP190b

SMC-185C

25ug

 

Cell Signaling, Oxidative Stress

HIF2 alpha Antibody

Antibodies

EP190B

SMC-185D

100ug

 

Cell Signaling, Oxidative Stress

Hinokitiol

Small Molecules

N/A

SIH-151-50MG

50mg

Iron Chelator antioxidant

Oxidative Stress

Hinokitiol

Small Molecules

N/A

SIH-151-250MG

250mg

Iron Chelator antioxidant

Oxidative Stress

HO-1 Antibody

Antibodies

1F12-A6

SMC-131C

25ug

 

Chaperones, Heat Shock, Organelle Markers, Oxidative Stress

HO-1 Antibody

Antibodies

1F12-A6

SMC-131D

100ug

 

Chaperones, Heat Shock, Organelle Markers, Oxidative Stress

HO-1 Antibody

Antibodies

N/A

SPC-112C

25ug

 

Chaperones, Heat Shock, Oxidative Stress

HO-1 Antibody

Antibodies

N/A

SPC-112D

100ug

 

Chaperones, Heat Shock, Oxidative Stress

HO-1 StressXpress® ELISA Kit

Kits

N/A

SKT-111

96-well

ELISA kit used to quantitate the HO-1 concentration in samples

Oxidative Stress

Idebenone

Small Molecules

N/A

SIH-150-20MG

20mg

Quinone antioxidant and free radical scavenger

Oxidative Stress

Idebenone

Small Molecules

N/A

SIH-150-100MG

100mg

Quinone antioxidant and free radical scavenger

Oxidative Stress

MCI-186

Small Molecules

N/A

SIH-152-50MG

50mg

MCI-186

Oxidative Stress

MCI-186

Small Molecules

N/A

SIH-152-250MG

250mg

MCI-187

Oxidative Stress

MDC1 Antibody

Antibodies

P2B11

SMC-197D

100ug

 

Oxidative Stress

Nitrotyrosine Antibody

Antibodies

39B6

SMC-154C

25ug

 

Cell Signaling, Oxidative Stress, Post-translational Modifications

Nitrotyrosine Antibody

Antibodies

39B6

SMC-154D

100ug

 

Cell Signaling, Oxidative Stress, Post-translational Modifications

Piperlongumine

Small Molecules

N/A

SIH-156-20MG

20mg

Apoptosis inducer in oxidative stressed cells

Oxidative Stress

Piperlongumine

Small Molecules

N/A

SIH-156-100MG

100mg

Apoptosis inducer in oxidative stressed cells

Oxidative Stress

Recombinant Human Mn SOD

Proteins

N/A

SPR-131A

50ug

 

Oxidative Stress

Recombinant Human Mn SOD

Proteins

N/A

SPR-131B

100ug

 

Oxidative Stress

Recombinant Human Mn SOD

Proteins

N/A

SPR-131C

2x100ug

 

Oxidative Stress

Recombinant Rat HO-1

Proteins

N/A

SPR-315A

50ug

 

Chaperones, Heat Shock, Oxidative Stress

Recombinant Rat HO-1

Proteins

N/A

SPR-315B

100ug

 

Chaperones, Heat Shock, Oxidative Stress

Recombinant Rat HO-1

Proteins

N/A

SPR-315C

2x100ug

 

Chaperones, Heat Shock, Oxidative Stress

Recombinant Rat Mn SOD

Proteins

N/A

SPR-130A

50ug

 

Oxidative Stress

Recombinant Rat Mn SOD

Proteins

N/A

SPR-130B

100ug

 

Oxidative Stress

Recombinant Rat Mn SOD

Proteins

N/A

SPR-130C

2x100ug

 

Oxidative Stress

SOD (Cu/Zn) Antibody

Antibodies

N/A

SPC-115C

25ug

 

Oxidative Stress

SOD (Cu/Zn) Antibody

Antibodies

N/A

SPC-115D

100ug

 

Oxidative Stress

SOD (Cu/Zn) Antibody

Antibodies

N/A

SPC-116C

25ug

 

Oxidative Stress

SOD (Cu/Zn) Antibody

Antibodies

N/A

SPC-116D

100ug

 

Oxidative Stress

SOD (EC) Antibody

Antibodies

4GG11G6

SMC-167C

25ug

 

Oxidative Stress

SOD (EC) Antibody

Antibodies

4GG11G6

SMC-167D

100ug

 

Oxidative Stress

SOD (Mn) Antibody

Antibodies

N/A

SPC-117C

25ug

 

Oxidative Stress

SOD (Mn) Antibody

Antibodies

N/A

SPC-117D

100ug

 

Oxidative Stress

SOD (Mn) Antibody

Antibodies

N/A

SPC-118C

25ug

 

Oxidative Stress

SOD (Mn) Antibody

Antibodies

N/A

SPC-118D

100ug

 

Oxidative Stress

TEMPO

Small Molecules

N/A

SIH-155-500MG

500mg

Stabilized free radical

Oxidative Stress