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Hygromycin B, EvoPure®

Description

Hygromycin B is an aminoglycoside antibiotic which targets both prokaryotic and eukaryotic cells.

We offer five forms of hygromycin B: hygromycin B (H007), hygromycin B, EvoPure® (H010), hygromycin B solution (H011), hygromycin B, EvoPure® solution (H015), and hygromycin B, concentrated solution (H001).

Hygromycin B (H007) and hygromycin B, EvoPure® (H010) are both freely soluble in aqueous solution. Hygromycin B solution (H011) is prepared at 50 mg/mL in PBS buffer. Hygromycin B, EvoPure® solution (H015) is prepared at 100 mg/mL. Hygromycin B, concentrated solution (H001) is prepared at 450,000 U/mL. EvoPure® products are purified single antibiotic fractions, most >99% pure.

Mechanism:
Toxicity of hygromycin B is thought to arise from inhibiting protein synthesis by strengthening the interaction of peptidyl-tRNA in the ribosomal acceptor (“A”) site preventing translocation by EF-2 (elongation factor 2).

Plant Biology Applications:
The toxicity of Hygromycin B and the availability of a selection marker (npt II) makes this antibiotic applicable as gene selection agent. This transformation system was successfully used by Dai and co-workers in rice (2001).

Form:
Powder

Purity Level:
≥99.5%

Price: (EUR)

Packaging: Regular Price: Promo Price:
2 x 1 g 264.00 93
1 x 10 g 1074.08 376.95
5 x 10 g 4940.77 1734.00

You can find more specifics about this product in our detailed brochure.