（BE102A）- HBsAb

Hepatitis B is an infectious illness caused by hepatitis B virus (HBV) which is an envelope, double-stranded DNA virus belonging to the Hepadnaviridae family and is recognized as the major cause of blood transmitted hepatitis together with hepatitis C virus (HCV). HBV is excreted in body fluids such as semen, saliva, blood and urine in persons with acute or chronic infection. The hepatitis B virus is known as a blood-borne virus because it is transmitted from one person to another via blood or fluids contaminated with blood. Transmission of hepatitis B virus results from exposure to infectious blood or body fluids.When HBV invades the body it causes liver damage through induction of auto-immunity. Three immunity has been found, surface antigen (HBsAg)/HBsAb, core antigen (HBcAg)/HBcAb and antigen (HBeAg)/HBeAb. As it is difficult to detect the core antigen in the serum, the other five are been done to diagnosing HBV. Hepatitis B “core” antigen (HBcAg) is a major component of the viral structure. Antibodies to HBcAg (anti-HBc total antibody, and IgM) appear shortly after the appearance of HBsAg and persist for life both in persons who have recovered from a hepatitis B infection and in those who develop HBsAg-carrier status but in rare cases, a HBV infection can also run its course without the appearance of immunologically detectable anti-HBc (usually in immunosuppressed patients). Anti-HBc is a marker of acute, chronic or resolved HBV infection and screening for anti-HBc provides with information on the prevalence of the disease in different groups. In the absence of other hepatitis B markers (HBsAg-negative persons), anti-HBc may be the only indication of an existing hepatitis B viral infection.

More info: （BE102A）- HBsAb

Quantity: 96 tests/kit x 5

Price: 246€

（BE103A）- HBeAg

The Hepatitis B e antigen is found to be related to Hepatitis B viral infection. HBeAg is usually found in the early phase of Hepatitis B viral infection. The titer of HBeAg rises rapidly during the period of virus replication. The presence of HBeAg correlates with increasing numbers of infectious viruses (Dane particles) and the presence of viral specific DNA polymerase in serum. During the HBeAg positive stage, hepatitis B patients are at increasing risk of transmitting the virus to their contacts. Persistent presence of HBeAg in the hepatitis B virus carrier is often associated with chronic active hepatitis.

More info: （BE103A）- HBeAg

Quantity: 96 tests/kit x 5

Price: 246€

（BE104A）- HBeAb

The presence of antibody against hepatitis B viral e antigen is used as an indicator for (1) early HBs antigenemia before the peak of viral replication and (2) early convalescence when HBeAg has declined below detectable levels.  It is also useful to confirm a seroconversion. The seroconversion from HBeAg positivity to anti-HBe positivity indicates a reduced level of infectious virus because virus replication has decreased.

More info:（BE104A）- HBeAb

Quantity: 96 tests/kit x 5

Price: 246€

（BE105A）- HBcAb

Hepatitis B is an infectious illness caused by hepatitis B virus (HBV) which is an envelope, double-stranded DNA virus belonging to the Hepadnaviridae family and is recognized as the major cause of blood transmitted hepatitis together with hepatitis C virus (HCV). HBV is excreted in body fluids such as semen, saliva, blood and urine in persons with acute or chronic infection. The hepatitis B virus is known as a blood-borne virus because it is transmitted from one person to another via blood or fluids contaminated with blood. Transmission of hepatitis B virus results from exposure to infectious blood or body fluids.When HBV invades the body it causes liver damage through induction of auto-immunity. Three immunity has been found, surface antigen (HBsAg)/HBsAb, core antigen (HBcAg)/HBcAb and antigen (HBeAg)/HBeAb. As it is difficult to detect the core antigen in the serum, the other five are been done to diagnosing HBV. Hepatitis B “core” antigen (HBcAg) is a major component of the viral structure. Antibodies to HBcAg (anti-HBc total antibody, and IgM) appear shortly after the appearance of HBsAg and persist for life both in persons who have recovered from a hepatitis B infection and in those who develop HBsAg-carrier status but in rare cases, a HBV infection can also run its course without the appearance of immunologically detectable anti-HBc (usually in immunosuppressed patients). Anti-HBc is a marker of acute, chronic or resolved HBV infection and screening for anti-HBc provides with information on the prevalence of the disease in different groups. In the absence of other hepatitis B markers (HBsAg-negative persons), anti-HBc may be the only indication of an existing hepatitis B viral infection.

More info: （BE105A）- HBcAb

Quantity: 96 tests/kit x 5

Price: 246€

（BE301A）- HAV IgM

This kit uses capture ELISA method to detect anti-HAV IgM. The purified mouse anti-human IgM (μchain) antibody is coated on the solid phase of multi-wells. A conjugate HAV-Ag is added to the coated wells after diluted sample added and incubated. Then horseradish peroxides labeled HAV-Ag is added. If HAV-IgM is present in the sample, a complex of Anti-μ-chain-HAV-IgM –HAV-Ag -labeled with HRP will form. Wash wells to remove other unbounded serum components, incubate with substrate (TMB) to form a colored product, and measure the absorbance at 450nm to indicate the presence or absence of HAV-IgM in the sample. The test is special, sensitive, reproducible and easy to operate.

More info: （BE301A）- HAV IgM

Quantity: 96 tests/kit x 5

Price: 223€

（BE401A）- HEV IgG

This kit employs solid phase, indirect ELISA method for detection of IgG antibodies to HEV (anti-HEV) in serum or plasma with two-step incubation procedure. Polystyrene micros well are pre-coated with purified activated recombinant HEV antigen. The HRP conjugated mouse anti human IgG (r chain) monoclonal antibody serves as tracer. TMB is substrate for HRP. The enzyme reaction with substrate TMB produces a color change, and the intensity of the absorbance at 450 nm indicates the presence or absence of Anti-HEV antibodies IgM in the sample.  The test is specific, sensitive, reproducible and easy to operate.  It is for blood screen of HEV infection.

More info: （BE401A）- HEV IgG

Quantity: 96 tests/kit x 5

Price: 252€

（BE402A）- HEV IgM

This kit employs solid phase, capture ELISA method for detection of IgM antibodies to HEV (anti-HEV) in serum or plasma with two-step incubation procedure. Polystyrene microwell is pre-coated with purified activated mouse anti human IgM (μ chain) monoclonal antibody. The HRP conjugated recombinant HEV antigen serves as tracer. TMB is substrate for HRP. The enzyme reaction with substrate TMB produces a color change, and the intensity of the absorbance at 450 nm indicates the presence or absence of Anti-HEV antibodies IgM in the sample. The test is specific, sensitive, reproducible and easy to operate.  It is for diagnosis of early infection and epidemic survey.

More info: （BE402A）- HEV IgM

Quantity: 96 tests/kit x 5

Price: 263€

（BE501A）- EBV IgA

Epstein-Barr virus, frequently referred to as EBV, is a member of the herpes virus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. In developed countries, 80 - 90% of the adult population has been infected by the virus.
EBV is associated with several diseases state where it may act as the direct agent or as one of several cofactors. These diseases include: Infectious Mononucleosis(IM), Nasopharyngeal carcinoma(NPC), Burkitt's lymphoma(BL), Lymph proliferative disease and lymphoma in the immunosuppressed, X-linked lymph proliferative syndrome, Chronic infectious mononucleosis, Oral leukoplakia in AIDS patients, and Chronic interstitial pneumonitis in AIDS patients. EB virus enters the body through the mouth and establishes a productive infection in the pharyngeal epithelial cells. B-cells become infected and are disseminated throughout the body via the bloodstream. During acute primary infection, IgA, IgM and IgG to VCA as well as IgG to EA(D) and MA are induced. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time.  NPC is a genetically restricted tumor; being most common in the Southern Chinese.100% of sera from undifferentiated NPC patients have high-titre antibodies to EB-viral antigens. As in BL, antibodies against VCA are at a 10 times geometric mean titre. IgG and IgA levels against EA (D) and VCA rise as the disease progress and may be used for screening and monitoring purposes. VCA and EA (D) IgA are also uniquely found in the saliva of NPC patients. This is an enzyme linked immunosorbent assay for the detection of EBV-VCA IgA antibodies in Human serum or plasma and is indicated as a screening test for serum or plasma.

More info: （BE501A）- EBV IgA

Quantity: 96 tests/kit x 5

Price: 287€

（BE601A）- Anti-HIV 1&2

Human Immunodeficiency Virus Type (HIV-1) has been isolated from patients with AIDS and AIDS-related complex (ARC). HIV-1 was thought to be the sole causive agent of these syndromes until 1986, when a second type of Human Immunodeficiency Virus (HIV-2) was isolated and also reported to cause AIDS. Since the initial discovery, more than 600 cases of HIV-2 infection have been documented worldwide, with over 40 cases of AIDS related to HIV-2.
Both viruses have the same morphology and lymphotropism, and the modes of transmission appear to be identical.  In addition, HIV-1 and HIV-2 genomes exhibit about 60% homology in conserved genes such as gag and pol.  Serologic studies have also shown that the core proteins of HIV-1 and HIV-2 display frequent cross-reactivity whereas the envelope proteins are more type-specific.
Despite this immunologic cross-reactivity, detection of antibodies to HIV-2 with any of the licensed HIV-1 enzyme immunoassays is highly variable.  This HIV-1/HIV-2 EIA was developed to detect antibodies to HIV-1 and /or HIV-2, for blood screening and diagnostic purposes.
Any specimen that reacts in an initial test with the HIV-1/HIV-2 EIA must be retested in duplicate with the other company’s HIV-1/HIV-2 EIA.  Repeatably reactive specimens may contain antibodies to either HIV-1 or HIV-2. Therefore, additional, more specific or supplemental tests for antibodies to both HIV-1 and HIV-2 such as immunoblot, immunofluorescence, radioimmuno-precipitation must be performed to verify presence of antibodies to HIV.

More info: （BE601A）- Anti-HIV 1&2

Quantity: 96 tests/kit x 5

Price: 233€

（BE701A）- HIV Ab/Ag

More info: （BE701A）- HIV Ab/Ag

Quantity: 96 tests/kit x 5