Gentaur's Products: Innovative and High Quality Peptide Toxins
Conantokin G
Catalog N : 08CON009
Conantokin G: toxin properties
Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B sub units of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT). This compound is currently being evaluated in phase II clinical trials under the name CGX-1007 by Cognetix Inc. It has been shown to be an effective antiepileptic agent in several animal models of seizures.
Product Specification
AA sequence: Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
Length (aa): 17
Formula: C88H138N26O44
Molecular Weight: 2264.23 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [93438-65-4]
Source: Synthetic
Purity rate: > 97 %
Price & Quantities
Reference # | Product name | Quantity (mg) |
08CON009-00500 | Conantokin G | 0.5 |
08CON009-01000 | Conantokin G | 1 |
Other quantities available upon request