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Gentaur's Products: Innovative and High Quality Peptide Toxins


 

Conantokin G



Catalog N :  08CON009


Conantokin G: toxin properties

Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B sub units of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT). This compound is currently being evaluated in phase II clinical trials under the name CGX-1007 by Cognetix Inc. It has been shown to be an effective antiepileptic agent in several animal models of seizures.

Product Specification

AA sequence: Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
Length (aa): 17
Formula: C88H138N26O44
Molecular Weight: 2264.23 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [93438-65-4]
Source: Synthetic 
Purity rate: > 97 %

Price & Quantities


Reference # Product name Quantity (mg)
08CON009-00500 Conantokin G 0.5
08CON009-01000 Conantokin G 1

Other quantities available upon request