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Gentaur's Products: Innovative and High Quality Peptide Toxins


 

GaTx1


Catalog N: 13GTX001
 

GaTx1: Toxin Properties

The GaTx1 peptide was originally isolated from the venom of Leiurus quinquestriatus hebraeus. This peptide is a potent and selective inhibitor of CFTR, an anion selective channel belonging to the ABC transporter superfamily. It was shown to block CFTR channels in a state dependent manner by acting from the internal face of the channel and it is supposed to be a non competitive inhibitor of ATP-dependent channel gating. GaTx1 is a valuable tool to explore the function of CFTR.

Product Specifications

AA sequence: Cys1-Gly-Pro-Cys4-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys15-Ala-Glu-Cys18-Cys19-Gly-Gly-Ile-Gly-Lys-Cys25-Tyr-Gly-Pro-Gln-Cys30-Leu-Cys32-Asn-Arg-NH2
Disulfide bonds between: Cys1-Cys18, Cys4-Cys25, Cys15-Cys30, and Cys19-Cys32
Length (aa): 34
Formula: C147H224N46O47S96
Molecular Weight: 3674.2 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: not available
Source: Synthetic

Price & Quantities


Reference # Product name Quantity (mg)
13GTX001-00100 GaTx1 0.1
13GTX001-00500 GaTx1 0.5
13GTX001-01000 GaTx1 1

Other quantities available upon request