Gentaur's Products: Innovative and High Quality Peptide Toxins
GsAF-II
Peptide properties
GsAF-II (also termed Kappa-theraphotoxin-Gr2c) was originally isolated from the venom of Grammostola rosea spider. This peptide toxin has antinociceptive and antiarrhythmic effects in mammals. The peptide is reported to block the following voltage-gated sodium channels: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with IC50 values of, respectively, 5.7, 12, 24, 4, 6.6 and 1.3 µM. This peptide also blocks hERG1 with an IC50 value of 4.7 µM.
Product specifications
AA sequence: Tyr-Cys2-Gln-Lys-Trp-Met-Trp-Thr-Cys9-Asp-Glu-Glu-Arg-Lys-Cys15-Cys16-Glu-Gly-Leu-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Lys-Lys-Ile-Glu-Trp-OH
(Disulfide bonds between Cys2-Cys16, Cys9-Cys21, and Cys15-Cys25)
Length (aa): 31
Formula: C176H261N47O45S7
Molecular Weight: 3979.78 Da
Appearance: White lyophilized solid
Solubility: aqueous buffer
CAS number: not available
Source: Synthetic
Prices & Quantities
| Reference # | Prodcut name | Quantity (mg) |
| 12GSF002-00100 | GsAF-II | 0.1 |
| 12GSF002-00500 | GsAF-II | 0.5 |
| 12GSF002-01000 | GsAF-II | 1 |
Other quantities available upon request
