Cryptococcus neoformans Antigen Test Kit

 

Cryptococcus neoformans (CN)


CN is the major causative agent of fungal meningoencephalitis in both immunocompromised and immunocompetent individuals. Cryptococcal meningitis, caused by CN, can cause up to 30% mortality in AIDS patients. Glucuronoxylomannan (GXM) is the major polysaccharide of the capsule of CN and is released to tissue during infection. GXM is an indicator for cryptococcal meningitis.
CN Antigen Detection is the EiAforthe detection of GXM antigen in human cerebrospinal fluid (CSF) or serum.

 

Test Procedure

 

 

Features

96 tests        ELISA microplate with breakable strips                       Rapid            Result within 1.5 hrs
Specimen   Cerebrospinal Fluid (CSF) or serum                            Sensitivity    96%
Marker         Glucuronoxylomannan antigen                                     Specificity    99%

 

Clinical Significance


Early Diagnosis Detection at the early stage of infection

Medication guidance Management of antifungal medication based on the diagnostic result Monitoring GXM level is used to assess the effectiveness of treatment.

 

 

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