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Pooled shRNA Screening Libraries


 

Achieve superior RNAi screens with enhanced potency, sequence-verified  shRNA pools and flexible delivery strategies. 

Greater confidence in your results
  • Every clone is sequence verified – eliminate unwanted background from mutations introduced in chip-based pools
  • More potent shRNA per gene – decrease false positive and false negative results
  • Equimolar pooling process - reduces variation between samples
Choose the best promoter for your cells
  • Select the optimal promoter for your target cell line with a choice of promoters- Choose from SFFV, hCMV, mCMV and more
Your choice of format
  • In vitro or in vivo pool formats.  Pools can be subdivided into minipools for lower complexity and higher representation for in vivo or other applications that require less complex pools
  • Choice of gene coverage - premade gene families or custom gene sets
  • Ready to use lentiviral particles or plasmid DNA format
Pool Deconvolution Service
  • NGS analysis service - send us your genomic DNA and receive counts for every shRNA construct
  • Optimized indexed primer kit available for NGS (Illumina platform)

 

Pooled screening libraries (plasmid or viral particle format)

Cat# Species Format Family Genes More information
TLH7002 Human Plasmid Phosphatases 255 Send request
TLH7102 Human Virus Phosphatases 255 Send request
TLH7004 Human Plasmid Ubiquitin ligases 146 Send request
TLH7104 Human Virus Ubiquitin ligases 146 Send request
TLH7032 Human Plasmid Cancer Metabolism 642 Send request
TLH7132 Human Virus Cancer Metabolism 642 Send request
TLH7051 Human Plasmid Kinases 951 Send request
TLH7151 Human Virus Kinases 951 Send request
TLH7034 Human Plasmid Druggable Genome 1971 Send request
TLH7134 Human Virus Druggable Genome 1971 Send request
TLH7033 Human Plasmid Whole Genome 18,455 Send request
TLH7133 Human Virus Whole Genome 18,455 Send request
TLH7009 Human Plasmid Epigenetics-related genes 406 Send request
TLH7109 Human Virus Epigenetics-related genes 406 Send request
TLM7010 Mouse Plasmid Epigenetics-related genes 311 Send request
TLM7110 Mouse Virus Epigenetics-related genes 311 Send request

 

Pooled screening libraries - Formatted as Mini pools of ~1000 shRNA

Cat# Species Format Family Genes More information
TLH7085 Human Plasmid Kinases 951 Send request
TLH7185 Human Virus Kinases 951 Send request
TLH7052 Human Plasmid Druggable Genome 1971 Send request
TLH7152 Human Virus Druggable Genome 1971 Send request

 

Promoter Selection and Multiplex NGS Kits

Cat# Product Name More information
TLN0005 Promoter Selection Kit (SFFV, hCMV, mCMV) (viral particles)
TRP0002 NGS Illumina Platform Primer kit for pZIP (12 Indexes)

 

Controls

Cat# Product Name More information
TLN7196 ZIP (SFFV) lentiviral shRNA-mir non-targeting control #1 (viral particles)
TLN7496 ZIP (hCMV) lentiviral shRNA-mir non-targeting control #1 (viral particles)
TLN7796 ZIP (mCMV) lentiviral shRNA-mir non-targeting control #1 (viral particles)
TLH7194 Human ZIP (SFFV) lentiviral shRNA-mir positive control - PLK1 (viral particles)
TLH7198 Human ZIP (SFFV) lentiviral shRNA-mir positive control - GAPDH (viral particles)