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Penicillin G, EvoPure®

Description

Penicillin is a member of the β-lactam antibiotics and was one of the first discovered antibiotics.

We offer four forms of penicillin: penicillin G, EvoPure (P044), penicillin G sodium salt (P006), penicillin G potassium (P028), and penicillin V potassium (P027). Penicillin G sodium salt and penicillin G potassium is sparingly soluble in aqueous solution (0.210 mg/mL). Penicillin V potassium is sparingly soluble in aqueous solution at 1 mg/mL.

Mechanism:
β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases.

Spectrum:
Penicillin is targets primarily gram positive bacteria including Staphylococcus and Streptococcus species

Microbiology Applications:
Penicillin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:

Streptococcus pneumoniae 0.004 µg/mL – 0.5 µg/mL
Streptococcus agalactiae 0.03 µg/mL – 0.06 µg/mL
For a complete list of penicillin MIC values, click here.
Mycoplasma Media Supplements
Penicillin can be used as a selective agent in several types of isolation media:

Mycoplasma Agar - Mycoplasma Supplement G

Mycoplasma Agar - Mycoplasma Supplement P

Form:
Powder

Price: (EUR)

Packaging: Regular Price: Promo Price:
1 x 100 mg 690.48 242.31