Hygromycin B, EvoPure®
Description
Hygromycin B is an aminoglycoside antibiotic which targets both prokaryotic and eukaryotic cells.
We offer five forms of hygromycin B: hygromycin B (H007), hygromycin B, EvoPure® (H010), hygromycin B solution (H011), hygromycin B, EvoPure® solution (H015), and hygromycin B, concentrated solution (H001).
Hygromycin B (H007) and hygromycin B, EvoPure® (H010) are both freely soluble in aqueous solution. Hygromycin B solution (H011) is prepared at 50 mg/mL in PBS buffer. Hygromycin B, EvoPure® solution (H015) is prepared at 100 mg/mL. Hygromycin B, concentrated solution (H001) is prepared at 450,000 U/mL. EvoPure® products are purified single antibiotic fractions, most >99% pure.
Mechanism:
Toxicity of hygromycin B is thought to arise from inhibiting protein synthesis by strengthening the interaction of peptidyl-tRNA in the ribosomal acceptor (“A”) site preventing translocation by EF-2 (elongation factor 2).
Plant Biology Applications:
The toxicity of Hygromycin B and the availability of a selection marker (npt II) makes this antibiotic applicable as gene selection agent. This transformation system was successfully used by Dai and co-workers in rice (2001).
Form:
Powder
Purity Level:
≥99.5%
Price: (EUR)
Packaging: | Regular Price: | Promo Price: |
2 x 1 g | 264.00 | 93 |
1 x 10 g | 1074.08 | 376.95 |
5 x 10 g | 4940.77 | 1734.00 |